郭宏雄
专业学位硕导
职称:副教授
025-83759335
学院:公共卫生学院
guohongxiong@jscdc.cn
专业:公共卫生
个人简介

受教育情况:

1991年9月-1996年6月,兰州大学,临床医学专业,本科

1996年9月-1999年6月,兰州大学,生物化学专业,硕士

2002年9月-2005年6月,北京协和医学院-清华大学医学部,免疫学专业,博士

 

主要工作经历:

1999年7月至2002年8月,广东医科大学,助教

2005年8月至今,江苏省疾病预防控制中心,研究员

 

研究方向:   微生物与免疫

 

主要科技成果:

1. 男性同性恋人群对江苏省艾滋病传播的影响及防制策略的研究,江苏省人民政府,科技进步三等奖,2012;

2. 江苏省HIV流行趋势预测预警和流行趋势及防制策略研究,江苏省医学会,科技进步二等奖,2012;

3.  SARS跨种传播的适应性进化机制和HIV-1重组及分子流行病学研究,镇江市人民政府 科技进步二等奖,2009。

 

代表性论文(近三年):

1. Peishan Lu, Xiuying Deng, Ying Hu, Hongxiong Guo. The genotype distribution and phylodynamic of measles viruses circulating in the east of China in postvaccine era, 2005–2017. Journal of Medical Virology,2021, https://doi.org/10.1002/jmv.26842.

2. Yuan Li, Xiangbo Fan, Guangqing Yu, Peinan Wei, Yong Wang, Hongxiong Guo. An acute gastroenteritis outbreak associated with breakfast contaminated with norovirus by asymptotic food handler at a kindergarten in Shenzhen, China. BMC Infect Dis. 2021 Jan 12;21(1):54.doi: 10.1186/s12879-021-05762-z. 

3. Min Li, Min Guo, Long Chen, Chaowang Zhu, Yuyi Xiao, Pei Li, Hongxiong Guo, Liang Chen, Wei Zhang, Hong Du. Isolation and Characterization of Novel Lytic Bacteriophages Infecting Epidemic Carbapenem-Resistant Klebsiella pneumoniae Strains. Front Microbiol, 2020;eCollection 2020.

4. Yin Yueqi, Zhou Ying, Lu Jing, Guo Hongxiong, Chen Jianshuang, Xuan Yan, Cheng Hao, Yuan Defu, Hu Haiyang, Xu Xiaoqin, Wang Bei, Fu Gengfeng. The identification of a novel HIV-1 second-generation recombinant form (CRF01_AE/CRF07_BC) among men who have sex with men in Jiangsu, China. Curr HIV Res. 2020;doi: 10.2174/1570162X18666201026143200.

5. Ying Hu, Xiuying Deng, Peishan Lu, Hongxiong Guo. Measles Virus Imported by International Traveler in Jiangsu Province of China, in 2018 and 2019. Can J Infect Dis Med Microbiol. 2020 Feb 8;2020:7318582. doi: 10.1155/2020/7318582. eCollection 2020.

6. Jianjun Wu, Zhongwang Hu, Hui Yao, Hai Wang, Yanhua Lei, Ping Zhong, Yi Feng, Hui Xing , Yuelan Shen, Lin Jin, Aiwen Liu, Yizu Qin, Lifeng Miao, Bin Su, Yibo Zhang, Hongxiong Guo.The inference of HIV-1 transmission direction between HIV-1 positive couples based on the sequences of HIV-1 quasi-species. BMC Infect Dis, 2019;19(1):566.

7.Yibo Zhang, Xiuying Deng, Qiang Chen, Hongxiong Guo. Molecular evolution of the major

capsid gene in human Norovirus GII.17. Journal of Public Health and Emergency. 2019;3(6):1-5.

8. Xiuying Deng, Ying Hu, Peishan Lu, Ming-Hao Zhou, Hongxiong Guo. The first outbreak of measles virus caused by imported genotype D8 in Jiangsu province of China. Braz J Infect Dis. 2019;23(1):66-69.

9. Yuanbao Liu, Zhihao Liu, Xiuying Deng, Ying Hu, Zhiguo Wang, Peishan Lu, Hongxiong Guo, Xiang Sun, Yan Xu, Fenyang Tang, Feng-Cai Zhu. Waning immunity of one-dose measles-mumps-rubella vaccine to mumps in children from kindergarten to early school age: a prospective study. Expert Rev Vaccines 2018 May;17(5):445-452.

10. Lei Zhang, Zhiguo Wang, Ying Hu, Xiuying Deng, Hongxiong Guo, Xiang Sun, Fenyang Tang, Minghao Zhou, Yuanbao Liu. Application of a mixture model to assess the effect of measles-mumps-rubella vaccine on the mumps epidemic in children from kindergarten to early school age in Jiangsu Province, China. Hum Vaccin Immunother. 2018;14(11):2654-2659.

11. Qian Bian, Jing Lu, Li Zhang, Ying Chi, Yan Li, Hongxiong Guo. Highly pathogenic avian influenza A virus H5N1 non-structural protein 1 is associated with apoptotic activation of the intrinsic mitochondrial pathway. Exp Ther Med. 2017 Nov;14(5):4041-4046.

12. Ying Hu, Peishan Lu, Xiuying Deng, Hongxiong Guo, Minghao Zhou. The declining antibody level of measles virus in China population, 2009-2015. BMC Public Health, 2018;18(1):906.

 

发表论文
教材专著
科研成果
目前承担的科研项目
近5年完成的科研项目

研究方向

微生物分子流行病学与免疫学